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Airway stenting for emphysema: back to the drawing board.

Abstract
In a recent report, authors describe their findings from the Exhale Airway Stents for Emphysema (EASE) trial. In this study, investigators follow patients with emphysema and severe hyperinflation after a novel bronchoscopic lung-volume reduction procedure utilizing paclitaxel-eluting stents. Despite the merits of this randomized, sham-controlled, multi-institutional study, the authors were unable to demonstrate any sustainable benefit for the treatment group upon follow-up. Nonetheless, important lessons can be learned from this trial, which has set a foundation for future investigations.
AuthorsMara B Antonoff, Jonathan D'Cunha
JournalSeminars in thoracic and cardiovascular surgery (Semin Thorac Cardiovasc Surg) Vol. 23 Issue 4 Pg. 263-5 ( 2011) ISSN: 1532-9488 [Electronic] United States
PMID22443642 (Publication Type: News)
CopyrightCopyright © 2011 Elsevier Inc. All rights reserved.
Chemical References
  • Respiratory System Agents
  • Paclitaxel
Topics
  • Bronchoscopy (instrumentation)
  • Drug-Eluting Stents
  • Humans
  • Paclitaxel (administration & dosage)
  • Prosthesis Design
  • Pulmonary Emphysema (physiopathology, surgery)
  • Respiratory System Agents (administration & dosage)
  • Treatment Outcome

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