Abstract | PURPOSE: SETTING: Sadalla Amin Ghanem Eye Hospital, Joinville, Santa Catarina, Brazil. DESIGN: Case series. METHODS:
Excimer laser corneal wavefront-guided PRK with intraoperative mitomycin-C (MMC) 0.02% was performed. Main outcome measures were uncorrected (UDVA) and corrected (CDVA) distance visual acuities, spherical equivalent (SE), corneal aberrations, and haze. RESULTS: The mean time between RK and PRK in the 61 eyes (39 patients) was 18.8 years ± 3.8 (SD). Before PRK, the mean SE was +4.17 ± 1.97 diopters (D); the mean astigmatism, -1.39 ± 1.04 D; and the mean CDVA, 0.161 ± 0.137 logMAR. At 24 months, the mean values were 0.14 ± 0.99 D (P<.001), -1.19 ± 1.02 D (P=.627), and 0.072 ± 0.094 logMAR (P<.001), respectively; the mean UDVA was 0.265 ± 0.196 (P<.001). The UDVA was 20/25 or better in 37.7% of eyes and 20/40 or better in 68.9%. The CDVA improved by 1 or more lines in 62.3% of eyes. Two eyes (3.3%) lost 2 or more lines, 1 due to corneal ectasia. Thirty eyes (49.2%) were within ± 0.50 D of intended SE and 45 (73.8%) were within ± 1.00 D. From 6 to 24 months, the mean SE regression was +0.39 D (P<.05). A significant decrease in coma, trefoil, and spherical aberration occurred. Three eyes developed peripheral haze more than grade 1. CONCLUSION: Corneal wavefront-guided PRK with MMC for hyperopia after RK significantly improved UDVA, CDVA, and higher-order corneal aberrations with a low incidence of visually significant corneal haze.
|
Authors | Ramon C Ghanem, Vinícius C Ghanem, Emir A Ghanem, Newton Kara-José |
Journal | Journal of cataract and refractive surgery
(J Cataract Refract Surg)
Vol. 38
Issue 4
Pg. 595-606
(Apr 2012)
ISSN: 1873-4502 [Electronic] United States |
PMID | 22440434
(Publication Type: Journal Article)
|
Copyright | Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Alkylating Agents
- Mitomycin
|
Topics |
- Adult
- Aged
- Alkylating Agents
(administration & dosage)
- Combined Modality Therapy
- Corneal Wavefront Aberration
(etiology, physiopathology, surgery)
- Female
- Follow-Up Studies
- Humans
- Hyperopia
(etiology, physiopathology, surgery)
- Keratotomy, Radial
- Lasers, Excimer
- Male
- Middle Aged
- Mitomycin
(administration & dosage)
- Photorefractive Keratectomy
- Postoperative Complications
- Prospective Studies
- Refraction, Ocular
(physiology)
- Visual Acuity
(physiology)
|