T-cell lymphoma/Sézary syndrome in a liver transplant recipient.

Abstract

BACKGROUND:

Cutaneous T-cell lymphoma is a rare subtype of posttransplantation lymphoproliferative disease, with only 29 cases reported in the literature to date, the majority of which are post-renal transplantation. Only a few were reported after pancreas, heart, and bone marrow transplantation. There have been no reports of cutaneous T-cell lymphoma following liver transplantation to date.

OBJECTIVE:

We report a case of a 76-year-old male who developed generalized eczematous eruption 13 years after a liver transplantation. Investigations showed that it was Epstein-Barr virus-negative, CD3-positive, and CD4-positive cutaneous T-cell lymphoma with Sézary cells in the blood.

CONCLUSION:

This shows that cutaneous T-cell lymphoma/Sézary syndrome can also develop after liver transplantation. To our knowledge, there are no similar reports in the English literature.

• Authors: Nojoud Al Ajroush, Khadija Rafique Sheikh, Razan Kadry, Abdulmonem Almutawa, Abdullah Alfadley
• Journal: Journal of cutaneous medicine and surgery (J Cutan Med Surg) 2012 Jan-Feb Vol. 16 Issue 1 Pg. 68-71 ISSN: 1203-4754 [Print] United States
• PMID: 22418000 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Eczema (etiology)
• Humans
• Immunohistochemistry
• Liver Cirrhosis (surgery)
• Liver Transplantation (adverse effects, immunology)
• Male
• Sezary Syndrome (diagnosis, etiology, immunology, metabolism, pathology)
• Skin Neoplasms (etiology, immunology, metabolism, pathology)
• Time Factors