Orthodontic treatment of a child with Crigler-Najjar syndrome type I using tacrolimus following liver transplantation.

Abstract	The present study reports the orthodontic treatment of a child with Crigler-Najjar syndrome type I following a liver transplant and administration of tacrolimus (1 mg/day). Tacrolimus (FK506) is fundamental to immunosuppression following transplantation. The child exhibited Class II division 1 malocclusion. The treatment option was to use a Herbst appliance for seven months and a fixed appliance (straight wire) for 12 months.
Authors	Joao Batista Novaes-Junior, Milene T Martins, Elizabeth M Lages, Miriam P Vale, Henrique Pretti, Saul M Paiva
Journal	General dentistry (Gen Dent) 2012 Mar-Apr Vol. 60 Issue 2 Pg. e114-8 ISSN: 0363-6771 [Print] United States
PMID	22414515 (Publication Type: Case Reports, Journal Article)
Chemical References	Immunosuppressive Agents Tacrolimus
Topics	Cephalometry Child Crigler-Najjar Syndrome (surgery) Humans Immunosuppressive Agents (therapeutic use) Liver Transplantation Male Malocclusion, Angle Class II (therapy) Orthodontic Appliances, Functional Orthodontic Wires Orthodontics, Corrective Radiography, Panoramic Retrognathia (therapy) Tacrolimus (therapeutic use) Treatment Outcome

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