Abstract | BACKGROUND: METHODS: RESULTS: Histopathology of the enucleated right eye showed a predominantly lymphocytic inflammatory infiltration with some plasma cells and epithelioid granulomata in the choroid, suggesting the diagnosis of SO. CONCLUSIONS: SO seems to be driven by T lymphocytes, specifically by the CD4 subset of T cells. HIV-infected individuals suffer a decline in CD4 T cell numbers, leading to an acquired immunodeficiency that could halt the development of the inflammatory reaction responsible for SO. The restoration of the CD4 counts by HAART therapy makes HIV-infected individuals as susceptible to SO as non-infected ones. To the best of our knowledge, there are no cases of SO in HIV-infected patients reported in the literature.
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Authors | Miguel A de la Fuente, Nicolas Alejandre, Patricia Ferrer, Gillermo Fernandez, Jose L Sarasa, Olga Sanchez |
Journal | Journal of ophthalmic inflammation and infection
(J Ophthalmic Inflamm Infect)
Vol. 2
Issue 3
Pg. 161-4
(Sep 2012)
ISSN: 1869-5760 [Electronic] Germany |
PMID | 22411458
(Publication Type: Journal Article)
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