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Intracameral mydriatics in phacoemulsification cataract surgery -- a 6-year follow-up.

AbstractPURPOSE:
To evaluate the long-term safety of intracameral mydriatics (ICM) in phacoemulsification cataract surgery compared with conventional topical mydriatics (TM).
METHODS:
A total of 45 patients were examined 6 years after phacoemulsification cataract surgery. The patients had previously participated in a prospective randomized double-blind study including 60 patients, operated with either ICM or TM. The follow-up included best-corrected visual acuity (BCVA), intraocular pressure (IOP), grade of posterior capsule opacification (PCO), YAG laser capsulotomy rate, pupil size, corneal thickness and endothelial morphology.
RESULTS:
No differences in postoperative BCVA, IOP, pupil size, PCO or YAG rate were observed between the groups. Endothelial cell loss, endothelial morphology and corneal thickness were also equivalent.
CONCLUSIONS:
Intracameral mydriatics is a safe alternative to topical mydriatics in phacoemulsification cataract surgery with no long-term disadvantages at 6-year follow-up.
AuthorsBjörn Lundberg, Anders Behndig
JournalActa ophthalmologica (Acta Ophthalmol) Vol. 91 Issue 3 Pg. 243-6 (May 2013) ISSN: 1755-3768 [Electronic] England
PMID22405257 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Copyright© 2012 The Authors. Acta Ophthalmologica © 2012 Acta Ophthalmologica Scandinavica Foundation.
Chemical References
  • Mydriatics
  • Ophthalmic Solutions
  • Phenylephrine
  • Lidocaine
  • Cyclopentolate
Topics
  • Administration, Topical
  • Aged
  • Anterior Chamber (drug effects)
  • Capsule Opacification (classification, pathology, surgery)
  • Cornea (drug effects)
  • Corneal Endothelial Cell Loss
  • Cyclopentolate (administration & dosage)
  • Double-Blind Method
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Humans
  • Intraocular Pressure (drug effects, physiology)
  • Laser Therapy
  • Lasers, Solid-State (therapeutic use)
  • Lens Implantation, Intraocular
  • Lidocaine (administration & dosage)
  • Male
  • Mydriatics (administration & dosage)
  • Ophthalmic Solutions
  • Phacoemulsification
  • Phenylephrine (administration & dosage)
  • Prospective Studies
  • Pupil (drug effects)
  • Visual Acuity (drug effects, physiology)

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