[Lyell's syndrome: proposal for a therapeutic protocol].

Abstract

Toxic epidermal necrolysis or Lyell's syndrome is a life-threatening, drug-induced disorder characterized by severe epidermal injury. Although plasmapheresis is expensive and requires easy venous access, it could be included in the first-line treatment of toxic epidermal necrolysis. The method is safe and effective, providing prompt relief from pain and rapid cessation of necrolysis. Moreover, in our experience plasmapheresis could be used in patients who were unresponsive to corticosteroids, and in patients with severe clinical symptoms.

• Authors: Maria Alma Posadinu, Emmanuela Sanna, Vanessa Canu, Milco Ciccarese, Pier Giorgio Pala, Maria Cossu
• Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia (G Ital Nefrol) 2012 Jan-Feb Vol. 29 Suppl 54 Pg. S147-8 ISSN: 0393-5590 [Print] Italy
• Vernacular Title: Sindrome di Lyell: proposta di un protocollo terapeutico.
• PMID: 22388849 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Diagnosis, Differential
• Female
• Humans
• Male
• Plasmapheresis
• Retrospective Studies
• Stevens-Johnson Syndrome (diagnosis, therapy)
• Treatment Outcome