Reactive arthritis after the intravesical instillation of BCG.

Abstract

The intravesical instilation of bacillus Calmette-Guérin (BCG) is a widely used and efficacious procedure for treatment of intermediate to high-grade superficial bladder cancer. The occurrence of osteoarticular side effects is infrequent compared to the number of administrated doses, and reactive arthritis is included within these effects. We present the case of a 54 years old HLA-27 (+) male, who developed reactive arthritis featuring asymmetric olygoarthritis and dactylitis after the second intravesical BCG instillation, which was resolved with administration of Etoricoxib and Isoniazid.

• Authors: Cristina Macía Villa, Walter Sifuentes Giraldo, Alina Boteanu, Mariano González Lanza, Javier Bachiller Corral
• Journal: Reumatologia clinica (Reumatol Clin) 2012 Sep-Oct Vol. 8 Issue 5 Pg. 284-6 ISSN: 1885-1398 [Electronic] Spain
• PMID: 22377450 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2011 Elsevier España, S.L. All rights reserved.

Chemical References

• BCG Vaccine
• HLA-B27 Antigen
• HLA-B7 Antigen

Topics

• Administration, Intravesical
• Arthritis, Reactive (etiology)
• BCG Vaccine (adverse effects, therapeutic use)
• Carcinoma, Transitional Cell (complications, surgery, therapy)
• Combined Modality Therapy
• Genetic Predisposition to Disease
• HLA-B27 Antigen (analysis)
• HLA-B7 Antigen (analysis)
• Humans
• Immunotherapy
• Instillation, Drug
• Male
• Middle Aged
• Urinary Bladder Neoplasms (complications, surgery, therapy)