Abstract | OBJECTIVE: STUDY DESIGN: Case series and chart review. SETTING: Tertiary care university-affiliated medical center. SUBJECTS AND METHODS: A total of 21 patients presented to our institution with ONB between 1997 and 2009. All records were reviewed for a history of preoperative hyponatremia or SIADH. RESULTS: Three patients were identified who had a history of SIADH prior to the diagnosis of ONB. Immunohistochemical staining of the tumor specimens from the 3 patients with SIADH was positive for arginine vasopressin. SIADH resolved in all 3 patients after successful treatment of ONB. CONCLUSION: Although uncommon, SIADH can be the presenting symptom of ONB and should be considered during the workup for idiopathic SIADH.
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Authors | Stacey T Gray, Eric H Holbrook, Mohammed H Najm, Peter M Sadow, William T Curry, Derrick T Lin |
Journal | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
(Otolaryngol Head Neck Surg)
Vol. 147
Issue 1
Pg. 147-51
(Jul 2012)
ISSN: 1097-6817 [Electronic] England |
PMID | 22368044
(Publication Type: Journal Article)
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Topics |
- Esthesioneuroblastoma, Olfactory
(complications)
- Female
- Humans
- Inappropriate ADH Syndrome
(diagnosis, etiology)
- Male
- Middle Aged
- Nasal Cavity
- Nose Neoplasms
(complications)
- Retrospective Studies
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