Abstract | INTRODUCTION: CASE REPORT: A 23-year-old Native American woman with a history of systemic lupus erythematosus and erosive polyarthritis treated with prednisone and etanercept presented with focal weakness, hemiataxia, diplopia, and dysarthria. Brain magnetic resonance imaging demonstrated progressive, T2 signal hyperintensities within the brainstem and cerebellar white matter without mass effect or gadolinium enhancement. Cerebrospinal fluid showed elevated protein and JC virus polymerase chain reaction positive with 28,600 copies/ml diagnostic of PML. CONCLUSIONS:
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Authors | Jonathan Graff-Radford, Maisha T Robinson, Rahma M Warsame, Eric L Matteson, Scott D Z Eggers, B Mark Keegan |
Journal | The neurologist
(Neurologist)
Vol. 18
Issue 2
Pg. 85-7
(Mar 2012)
ISSN: 2331-2637 [Electronic] United States |
PMID | 22367837
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Immunoglobulin G
- Immunosuppressive Agents
- Receptors, Tumor Necrosis Factor
- Etanercept
- Prednisone
|
Topics |
- Drug Therapy, Combination
(adverse effects)
- Etanercept
- Female
- Humans
- Immunocompromised Host
- Immunoglobulin G
(adverse effects)
- Immunosuppressive Agents
(adverse effects)
- Leukoencephalopathy, Progressive Multifocal
(chemically induced, virology)
- Lupus Erythematosus, Systemic
(drug therapy)
- Prednisone
(adverse effects)
- Receptors, Tumor Necrosis Factor
- Young Adult
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