Acute generalized exanthematous pustulosis caused by daptomycin.

Abstract

Daptomycin, a lipopeptide antibiotic with similar action as vancomycin, is used to treat complicated skin and soft tissue infections caused by resistant Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, penicillin-resistant streptococci, and vancomycin-resistant enterococci. Acute generalized exanthematous pustulosis (AGEP), characterized by acute onset of numerous sterile, nonfollicular pinhead sized pustules, is common secondary to drugs, in particular, antibiotics. We present the first case of AGEP following the use of daptomycin.

• Authors: Teoh Yee Leng, Mark Koh Jean Aan, Michelle Chan, Liu Tsun Tsien
• Journal: Annals of dermatology (Ann Dermatol) Vol. 23 Issue Suppl 3 Pg. S288-9 (Dec 2011) ISSN: 2005-3894 [Electronic] Korea (South)
• PMID: 22346259 (Publication Type: Case Reports)