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Comparison of the effect of four decalcifying agents combined with 60°C 3% sodium hypochlorite on smear layer removal.

AbstractINTRODUCTION:
The objective of this study was to compare the efficacy on smear layer removal of 4 decalcifying agents: 17% ethylenediaminetetraacetic acid (EDTA), 20% citric acid, BioPure MTAD, and SmearClear.
METHODS:
Forty-five single-rooted human teeth were used and prepared up to ProTaper F3. After each instrumentation, 1 mL of 3% NaOCl at 60°C was irrigated for 1 minute. All the samples were randomly divided into 5 groups according to the final irrigants: 17% EDTA, 20% citric acid, BioPure MTAD, SmearClear, and 3% NaOCl (control). The smear layer removal of all groups at the apical, middle, and coronal thirds was observed under the thermal field emission scanning electron microscope.
RESULTS:
The EDTA group was significantly more effective than the SmearClear and MTAD groups (P < .05). The efficacy of all three thirds in the EDTA, MTAD, and SmearClear groups can be arranged as coronal, middle, and apical thirds (P < .05) from excellent to poor. However, in the citric acid group, the coronal two thirds were significantly better than the apical third (P < .05), and there was no statistical significance between the coronal and middle thirds (P > .05).
CONCLUSIONS:
The 4 decalcifying agents could effectively, but not completely, remove the smear layer, especially in the apical third. The efficacy of 17% EDTA was better than that of MTAD and SmearClear.
AuthorsLigeng Wu, Ying Mu, Xiuli Deng, Shasha Zhang, Dongyan Zhou
JournalJournal of endodontics (J Endod) Vol. 38 Issue 3 Pg. 381-4 (Mar 2012) ISSN: 1878-3554 [Electronic] United States
PMID22341079 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
Chemical References
  • MTAD (intracanal irrigant)
  • Polysorbates
  • Root Canal Irrigants
  • Smear Clear
  • Citric Acid
  • Edetic Acid
  • Sodium Hypochlorite
  • Doxycycline
Topics
  • Citric Acid (pharmacology)
  • Dental Pulp Cavity (drug effects, ultrastructure)
  • Dentin (drug effects, ultrastructure)
  • Double-Blind Method
  • Doxycycline (pharmacology)
  • Edetic Acid (pharmacology)
  • Humans
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Polysorbates (pharmacology)
  • Root Canal Irrigants (pharmacology)
  • Root Canal Preparation (instrumentation)
  • Smear Layer
  • Sodium Hypochlorite (pharmacology)
  • Tooth Apex (drug effects, ultrastructure)

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