Comparison of the effect of four decalcifying agents combined with 60°C 3% sodium hypochlorite on smear layer removal.

The objective of this study was to compare the efficacy on smear layer removal of 4 decalcifying agents: 17% ethylenediaminetetraacetic acid (EDTA), 20% citric acid, BioPure MTAD, and SmearClear.
Forty-five single-rooted human teeth were used and prepared up to ProTaper F3. After each instrumentation, 1 mL of 3% NaOCl at 60°C was irrigated for 1 minute. All the samples were randomly divided into 5 groups according to the final irrigants: 17% EDTA, 20% citric acid, BioPure MTAD, SmearClear, and 3% NaOCl (control). The smear layer removal of all groups at the apical, middle, and coronal thirds was observed under the thermal field emission scanning electron microscope.
The EDTA group was significantly more effective than the SmearClear and MTAD groups (P < .05). The efficacy of all three thirds in the EDTA, MTAD, and SmearClear groups can be arranged as coronal, middle, and apical thirds (P < .05) from excellent to poor. However, in the citric acid group, the coronal two thirds were significantly better than the apical third (P < .05), and there was no statistical significance between the coronal and middle thirds (P > .05).
The 4 decalcifying agents could effectively, but not completely, remove the smear layer, especially in the apical third. The efficacy of 17% EDTA was better than that of MTAD and SmearClear.
AuthorsLigeng Wu, Ying Mu, Xiuli Deng, Shasha Zhang, Dongyan Zhou
JournalJournal of endodontics (J Endod) Vol. 38 Issue 3 Pg. 381-4 (Mar 2012) ISSN: 1878-3554 [Electronic] United States
PMID22341079 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
Chemical References
  • MTAD (intracanal irrigant)
  • Polysorbates
  • Root Canal Irrigants
  • Smear Clear
  • Citric Acid
  • Edetic Acid
  • Sodium Hypochlorite
  • Doxycycline
  • Citric Acid (pharmacology)
  • Dental Pulp Cavity (drug effects, ultrastructure)
  • Dentin (drug effects, ultrastructure)
  • Double-Blind Method
  • Doxycycline (pharmacology)
  • Edetic Acid (pharmacology)
  • Humans
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Polysorbates (pharmacology)
  • Root Canal Irrigants (pharmacology)
  • Root Canal Preparation (instrumentation)
  • Smear Layer
  • Sodium Hypochlorite (pharmacology)
  • Tooth Apex (drug effects, ultrastructure)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: