[Ghrelin secretion in patients, operated on cholelithiasis].

Abstract

The grelin blood level was measured on 54 patients, of whom 18 were healthy volunteers; 20 patients with cholecystolithiasis had been measured perioperatively during the cholecystectomy; and the rest 16 patients of the study group had had cholecystectomy 2-15 years ago. All patients demonstrated perioperative hypergrelinemy with the normalization of the grelin level during the long-term follow-up. Grelin is considered to have certain immunomodulating and anti-inflammatory effects, thus improving the postoperative regeneration. Therefore, the increase of grelin blood level during the perioperative period is considered to be a defense reaction.

• Authors: I V Tereshchenko, P E Kaiushev
• Journal: Khirurgiia (Khirurgiia (Mosk)) Issue 10 Pg. 39-42 ( 2011) ISSN: 0023-1207 [Print] Russia (Federation)
• PMID: 22334903 (Publication Type: English Abstract, Journal Article)

Chemical References

• Ghrelin

Topics

• Adult
• Cholecystectomy (adverse effects, methods)
• Cholelithiasis (surgery)
• Female
• Follow-Up Studies
• Ghrelin (blood)
• Humans
• Immunomodulation
• Inflammation (etiology, metabolism)
• Male
• Perioperative Care (methods)
• Postoperative Complications (etiology, immunology, metabolism)
• Postoperative Period
• Time
• Wound Healing