HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

FluxEXPLORER: a new high-speed laser Doppler imaging system for the assessment of burn injuries.

AbstractBACKGROUND:
Deep burn assessment made by clinical evaluation has an accuracy varying between 60% and 80% and will determine if a burn injury will need tangential excision and skin grafting or if it will be able to heal spontaneously. Laser Doppler Imaging (LDI) techniques allow an improved burn depth assessment but their use is limited by the time-consuming image acquisition which may take up to 6 min per image.
METHODS:
To evaluate the effectiveness and reliability of a newly developed full-field LDI technology, 15 consecutive patients presenting with intermediate depth burns were assessed both clinically and by FluxExplorer LDI technology. Comparison between the two methods of assessment was carried out.
RESULTS:
Image acquisition was done within 6 s. FluxEXPLORER LDI technology achieved a significantly improved accuracy of burn depth assessment compared to the clinical judgement performed by board certified plastic and reconstructive surgeons (P < 0.05, 93% of correctly assessed burns injuries vs. 80% for clinical assessment).
CONCLUSION:
Technological improvements of LDI technology leading to a decreased image acquisition time and reliable burn depth assessment allow the routine use of such devices in the acute setting of burn care without interfering with the patient's treatment. Rapid and reliable LDI technology may assist clinicians in burn depth assessment and may limit the morbidity of burn patients through a minimization of the area of surgical debridement. Future technological improvements allowing the miniaturization of the device will further ease its clinical application.
AuthorsPaolo Erba, Daniel Espinoza, Nathalie Koch, Thierry Christen, Alexandre Serov, Wassim Raffoul
JournalSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (Skin Res Technol) Vol. 18 Issue 4 Pg. 456-61 (Nov 2012) ISSN: 1600-0846 [Electronic] England
PMID22332947 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Copyright© 2012 John Wiley & Sons A/S.
Topics
  • Adolescent
  • Adult
  • Aged
  • Burns (diagnosis)
  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Image Enhancement (instrumentation, methods)
  • Laser-Doppler Flowmetry (instrumentation, methods)
  • Middle Aged
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Skin (injuries, pathology)
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: