[Analysis of using Danhong injection to treatment coronary heart disease patients medicines based on real world HIS database].

Abstract

OBJECTIVE:

To analyze the rules of medicinal groups that doctors treat angina pectoris using Danhong injection.

METHOD:

Two thousands and seventy cases from hospital information system of 10 hospitals in Beijing 3a grade hospital were collected. Then use frequencies to find the most common drug and use association rules with apriori algorithm to analyze doctor's prescription compatibility rules curing coronary heart disease.

RESULT:

The compatibility among aspirin, oral nitrate, oral dose of clopidogrel and oral dose of Xintong was the most frequently used medicinal groups with Danhong injection in real world HIS database.

CONCLUSION:

Danhong injection was used at treatment of coronary heart disease is often combination with similar pharmacological effects chemical drugs. Doctors should balance the benefits and the risks.

• Authors: Jing Du, Wei Yang, Danhui Yi, Yanming Xie, Wei Yang, Yan Zhuang, Qian Chen
• Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (Zhongguo Zhong Yao Za Zhi) Vol. 36 Issue 20 Pg. 2821-4 (Oct 2011) ISSN: 1001-5302 [Print] China
• PMID: 22292375 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Drugs, Chinese Herbal
• danhong

Topics

• Coronary Artery Disease (drug therapy)
• Databases, Factual
• Drug Therapy, Combination
• Drugs, Chinese Herbal (administration & dosage, therapeutic use)
• Hospital Information Systems
• Humans
• Injections