Effects of methylphenidate on adolescents with aggressive conduct disorder and ADDH: a preliminary report.

Abstract

The effect of methylphenidate on aggression in adolescents diagnosed with both aggressive conduct disorder and attention deficit disorder with hyperactivity was assessed in nine male adolescents. After three open trials, a placebo controlled double-blind design was used. During methylphenidate treatment of the six double-blind subjects, there was a significant reduction of aggressivity (p's less than 0.05), as measured by the Adolescent Antisocial Behavior Checklist. Conners Teacher Rating Scale Hyperactivity and Aggression scores were in the predicted directions, but the differences were not statistically significant.

• Authors: S L Kaplan, J Busner, S Kupietz, E Wassermann, B Segal
• Journal: Journal of the American Academy of Child and Adolescent Psychiatry (J Am Acad Child Adolesc Psychiatry) Vol. 29 Issue 5 Pg. 719-23 (Sep 1990) ISSN: 0890-8567 [Print] United States
• PMID: 2228924 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Methylphenidate

Topics

• Adolescent
• Aggression (drug effects)
• Attention Deficit Disorder with Hyperactivity (drug therapy)
• Double-Blind Method
• Humans
• Male
• Methylphenidate (therapeutic use)
• Social Environment