Abstract |
A 29-year old man is admitted in our hospital for a dry cough which appeared a few weeks earlier and is now associated with a breath depending thoracic pain. As an engineer, he is realizing a thesis about the sound waves produced by coughing and is therefore frequently exposed to patients with various pulmonary infections. The chest X-ray, presents predominant pulmonary infiltrates on the periphery of the upper fields of the lungs. Blood analysis revealed a hypereosinophilia of 4.650/microl. The various bacteriological, parasitic and viral investigation tests are negative. The bronchioalveolar washing reveals more than 50% eosinophils. Exclusive pulmonary impairment and lack of autoantibody moved us to the diagnosis of chronic eosinophilic pneumonia (or Carrington syndrome). Corticosteroids were started at the dosis of 0,5 mg/kg of methyl- prednisolone. Clinical and biological features improved amazingly within 48 hours. This case report illustrates the overlap between the chronic eosinophilic pneumonia and the Churg-Strauss desease who can be considered as variants of the hypereosinophilic syndrome (HES). Therefore, the use of anti-interleukin-5 antibodies, already used in the SHE and Churg-Strauss syndrome, might be useful in this case.
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Authors | C Wachters, M Hildebrand |
Journal | Revue medicale de Bruxelles
(Rev Med Brux)
2011 Nov-Dec
Vol. 32
Issue 6
Pg. 536-9
ISSN: 0035-3639 [Print] Belgium |
Vernacular Title | Pneumonie, quand les ondes sonores s'en mêlent. |
PMID | 22279854
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Algorithms
- Churg-Strauss Syndrome
(complications, diagnostic imaging, drug therapy)
- Cough
(complications, diagnostic imaging, drug therapy)
- Diagnosis, Differential
- Humans
- Hypereosinophilic Syndrome
(complications, diagnostic imaging, drug therapy)
- Male
- Pneumonia
(diagnostic imaging, drug therapy, etiology)
- Pulmonary Eosinophilia
(complications, diagnostic imaging, drug therapy)
- Radiography, Thoracic
- Sound
(adverse effects)
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