Spontaneous esophageal perforation in a patient with mixed connective tissue disease.

Abstract

Spontaneous esophageal perforation is a rare and life-threatening disorder. Failure to diagnosis within the first 24-48 hours of presentation portends a poor prognosis. A patient with mixed connective tissue disease (MCTD) on low-dose prednisone and methotrexate presented moribund with chest and shoulder pain, a left hydropneumothorax, progressive respiratory failure and shock. Initial management focussed on presumed community acquired pneumonia (CAP) in a patient on immunosuppressants. Bilateral yeast empyemas were treated and attributed to immunosuppression. On day 26, the patient developed mediastinitis, and the diagnosis of esophageal perforation was first considered. A review of the literature suggests that the diagnosis and management of spontaneous esophageal perforation could have been more timely and the outcome less catastrophic.

• Authors: David Lyman
• Journal: The open rheumatology journal (Open Rheumatol J) Vol. 5 Pg. 138-43 ( 2011) ISSN: 1874-3129 [Electronic] United Arab Emirates
• PMID: 22279514 (Publication Type: Journal Article)