HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Factors and markers of virulence in Escherichia coli from human septicemia.

Abstract
One hundred Escherichia coli isolates from human septicemia were characterized with respect to O serogroups 1, 2, 4, 6, 7, 8, 15, 18, 75 and 78, alpha-hemolysin, carboxylesterase B typing, cytotoxic necrotizing factor, F165 and CS31A fimbrial antigens, aerobactin production, colicins, and antibiotic sensitivity. A factorial analysis of correspondence and chi 2 tests indicated that most of E. coli isolates belonging to the studied O serogroups were positive for the virulence factors or markers alpha-haemolysin, carboxylesterase B2 type, cytotoxic necrotizing factor, F165 fimbrial antigen and were antibiotic-sensitive (Group I). These characteristics differentiated them from E. coli isolates from other O serogroups which were generally antibiotic resistant and negative for the cited virulence factors and markers (Group II). Aerobactin and colicin production did not differentiate the two E. coli groups. E. coli O serogroups 4 and 6 were highly represented in group I and were responsible for most of the differences between the two groups.
AuthorsA Cherifi, M Contrepois, B Picard, P Goullet, J de Rycke, J Fairbrother, J Barnouin
JournalFEMS microbiology letters (FEMS Microbiol Lett) Vol. 58 Issue 3 Pg. 279-83 (Aug 1990) ISSN: 0378-1097 [Print] England
PMID2227363 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Antigens, Bacterial
  • Bacterial Toxins
  • Biological Factors
  • Cytotoxins
  • Escherichia coli Proteins
  • Hemolysin Proteins
  • cytotoxic necrotizing factor type 1
  • Carboxylic Ester Hydrolases
  • Carboxylesterase
Topics
  • Anti-Bacterial Agents (pharmacology)
  • Antigens, Bacterial (analysis)
  • Bacterial Toxins (immunology)
  • Bacterial Typing Techniques
  • Biological Factors
  • Carboxylesterase
  • Carboxylic Ester Hydrolases (immunology)
  • Cytotoxins (immunology)
  • Escherichia coli (classification, immunology, pathogenicity)
  • Escherichia coli Infections (immunology)
  • Escherichia coli Proteins
  • Factor Analysis, Statistical
  • Hemolysin Proteins (immunology)
  • Humans
  • Microbial Sensitivity Tests
  • Sepsis (microbiology)
  • Virulence

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: