Primitive neuroectodermal tumor of the heart.

Abstract

We present a case of primitive neuroectodermal tumor of the left atrium with involvement of the coronary sinus. The initial presentation was of cardiac tamponade resulting from the size of the tumor. There was no evidence of tumor elsewhere, and after complete resection and without adjuvant chemotherapy the patient is well at 2-year follow-up. There has been no evidence of tumor recurrence. This is a rare reported case of resection of a cardiac primitive neuroectodermal tumor without adjuvant chemotherapy. Other cases in the literature have been treated by orthoptic transplantation and resection with chemotherapy.

• Authors: Nnamdi Nwaejike, Doris Rassl, Hugo Ford, Stephen R Large
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 93 Issue 2 Pg. e27-9 (Feb 2012) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 22269764 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Chemical References

• Biomarkers, Tumor
• EWS-FLI fusion protein
• Oncogene Proteins, Fusion
• Proto-Oncogene Protein c-fli-1
• RNA-Binding Protein EWS

Topics

• Adult
• Biomarkers, Tumor (analysis, genetics)
• Cardiac Tamponade (etiology)
• Cesarean Section
• Coronary Sinus (pathology)
• Dyspnea (etiology)
• Edema (etiology)
• Female
• Heart Atria (pathology)
• Heart Neoplasms (chemistry, complications, genetics, pathology, surgery)
• Humans
• Magnetic Resonance Imaging
• Neuroectodermal Tumors (chemistry, complications, genetics, pathology, surgery)
• Oncogene Proteins, Fusion (genetics)
• Pericardial Effusion (etiology)
• Postoperative Complications (pathology, surgery)
• Proto-Oncogene Protein c-fli-1 (genetics)
• Puerperal Disorders (pathology, surgery)
• RNA-Binding Protein EWS (genetics)
• Remission Induction