Long-pulsed 1064-nm Nd:YAG laser significantly improves keratosis pilaris: a randomized, evaluator-blind study.

Abstract

BACKGROUND:

Keratosis pilaris (KP) is a very common disorder; yet, very few treatment options are available.

OBJECTIVES:

To evaluate the efficacy of long-pulsed 1064-nm Nd:YAG laser for the treatment of KP.

MATERIALS AND METHODS:

Eighteen patients with untreated KP on the upper outer arms were enrolled in a randomized clinical trial. One arm was treated with long-pulsed 1064-nm Nd:YAG laser at 30 msec pulse width and fluence of 34 J/cm(2), while the contralateral arm served as control. Patients received three consecutive treatments at 4-week intervals. Three blinded dermatologists assessed digital photographs using a quartile grading system to separately rate global improvement, erythema and the number of keratotic papules.

RESULTS:

Seventeen patients completed the study. There were statistically significant improvements in global assessment, erythema and the number of keratotic papules at 4 weeks after the last treatment (p < 0.05). All patients also stated that their lesions improved and were satisfied with the laser treatment.

CONCLUSION:

Long-pulsed 1064-nm Nd:YAG laser has been shown to improve KP in Thai patients compared with control after three treatment sessions.

• Authors: Pichai Saelim, Marisa Pongprutthipan, Suwimon Pootongkam, Vorapicha Jariyasethavong, Pravit Asawanonda
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 24 Issue 4 Pg. 318-22 (Aug 2013) ISSN: 1471-1753 [Electronic] England
• PMID: 22268726 (Publication Type: Journal Article, Randomized Controlled Trial)

Topics

• Abnormalities, Multiple (physiopathology, surgery)
• Adolescent
• Adult
• Darier Disease (physiopathology, surgery)
• Erythema (physiopathology)
• Eyebrows (abnormalities, physiopathology)
• Female
• Humans
• Lasers, Solid-State (therapeutic use)
• Male
• Treatment Outcome
• Young Adult