Abstract |
Stroke rehabilitation with different exercise paradigms has been investigated, but a comparison study on motor recovery after voluntary, involuntary, and forced exercises is limited. The current study used a rat brain ischemia model to investigate the effects of voluntary wheel running, involuntary muscle movement caused by functional electrical stimulation (FES), and forced treadmill exercise on motor recovery and brain BDNF changes. The results showed that voluntary exercise is the most effective intervention in upregulating the hippocampal BDNF level, and facilitating motor recovery after brain ischemia.
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Authors | Zheng Ke, Shea-Ping Yip, Le Li, Xiao-Xiang Zheng, Wing-Kin Tam, Kai-Yu Tong |
Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
(Annu Int Conf IEEE Eng Med Biol Soc)
Vol. 2011
Pg. 8223-6
( 2011)
ISSN: 2694-0604 [Electronic] United States |
PMID | 22256251
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Brain-Derived Neurotrophic Factor
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Topics |
- Animals
- Behavior, Animal
- Brain-Derived Neurotrophic Factor
(metabolism)
- Disease Models, Animal
- Male
- Motor Activity
(physiology)
- Physical Conditioning, Animal
- Rats
- Rats, Sprague-Dawley
- Recovery of Function
(physiology)
- Stroke
(physiopathology)
- Stroke Rehabilitation
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