Treatment of folliculitis decalvans with tacrolimus ointment.

Abstract

Folliculitis decalvans is an embarrassing and challenging disease with no established treatment guidelines. In this paper, we described four patients with this disease treated successfully with Tacrolimus ointment. All of them showed significant control of the condition, stopping inflammatory lesions and progression of the disease, although weak transitory outbreaks of inflammatory lesions were observed in some cases. Alopecia and tufted hairs remained unchanged. The discontinuation of the therapy produced rapid relapses in all cases. Close monitoring of these patients is recommended due to the potential risk of malignant transformation of the disease.

• Authors: Jesús Bastida, Pedro Valerón-Almazán, Néstor Santana-Molina, Carolina Medina-Gil, Gregorio Carretero-Hernández
• Journal: International journal of dermatology (Int J Dermatol) Vol. 51 Issue 2 Pg. 216-20 (Feb 2012) ISSN: 1365-4632 [Electronic] England
• PMID: 22250634 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2012 The International Society of Dermatology.

Chemical References

• Immunosuppressive Agents
• Ointments
• Tacrolimus

Topics

• Adult
• Female
• Folliculitis (drug therapy, pathology)
• Humans
• Immunosuppressive Agents (therapeutic use)
• Male
• Ointments
• Scalp Dermatoses (drug therapy, pathology)
• Tacrolimus (therapeutic use)
• Treatment Outcome
• Young Adult