Abstract | BACKGROUND: Functional dyspepsia (FD) is a common disease without an established optimal treatment. AIM: To determine (i) the effect of acupuncture in relieving FD symptoms and improving life quality; (ii) the effect difference between acupoint and non- acupoint; and (iii) the effect difference among different acupoints. METHODS: A total of 712 eligible patients were included and randomly assigned to six groups (Group A: specific acupoints of the stomach meridian; Group B: non-specific acupoints of the stomach meridian; Group C: specific acupoints of alarm and transport points; Group D: specific acupoints of the gallbladder meridian; Group E: sham acupuncture of non- acupoints; and Group F: itopride). A treatment period of 4 weeks (continuous five sessions per week), and a follow-up period of 12 weeks were arranged. The outcomes were the (i) patients' response, (ii) symptoms improvement measured using the Symptom Index of Dyspepsia and (iii) quality-of-life improvement based on Nepean Dyspepsia Index. RESULTS: All groups had an improvement in dyspepsia symptoms and the QoL at the end of treatment, and the improvement was sustained for 4 weeks and 12 weeks. The overall response rate was significantly higher in acupuncture group A (70.69%), and lower in sham acupuncture group (34.75%), compared with itopride and other acupuncture groups. Similarly, the difference in symptoms and QoL improvement was significant between group A and the other acupuncture groups. CONCLUSIONS: Acupuncture is effective in the treatment of functional dyspepsia, and is superior to non- acupoint puncture. The benefit of acupuncture relies on acupoint specificity.
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Authors | T T Ma, S Y Yu, Y Li, F R Liang, X P Tian, H Zheng, J Yan, G J Sun, X R Chang, L Zhao, X Wu, F Zeng |
Journal | Alimentary pharmacology & therapeutics
(Aliment Pharmacol Ther)
Vol. 35
Issue 5
Pg. 552-61
(Mar 2012)
ISSN: 1365-2036 [Electronic] England |
PMID | 22243034
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | © 2012 Blackwell Publishing Ltd. |
Topics |
- Acupuncture Points
- Acupuncture Therapy
(methods)
- Adult
- Dyspepsia
(physiopathology, therapy)
- Female
- Humans
- Male
- Meridians
- Middle Aged
- Quality of Life
- Severity of Illness Index
- Time Factors
- Treatment Outcome
- Young Adult
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