Acquired angioedema with C1 inhibitor deficiency associated with anticardiolipin antibodies.

Abstract

Acquired angioedema (AAE) with C1 inhibitor deficiency is often associated to B cell lymphoproliferative disorders or autoimmune diseases. We report a case of AAE associated with IgM anti-cardiolipin antibodies, with frequent edematous attacks, that disappeared completely after a slight immunosuppression and danazol therapy.

• Authors: E Di Leo, E Nettis, V Montinaro, G Calogiuri, P Delle Donne, A Ferrannini, A Vacca
• Journal: International journal of immunopathology and pharmacology (Int J Immunopathol Pharmacol) 2011 Oct-Dec Vol. 24 Issue 4 Pg. 1115-8 ISSN: 0394-6320 [Print] England
• PMID: 22230421 (Publication Type: Case Reports, Letter)

Chemical References

• Antibodies, Anticardiolipin
• Complement C1 Inactivator Proteins
• Complement C1 Inhibitor Protein
• Immunoglobulin M
• Immunosuppressive Agents
• SERPING1 protein, human
• Azathioprine
• Danazol
• Ticlopidine

Topics

• Aged
• Angioedema (diagnosis, drug therapy, immunology)
• Antibodies, Anticardiolipin (blood)
• Azathioprine (therapeutic use)
• Complement C1 Inactivator Proteins (deficiency)
• Complement C1 Inhibitor Protein
• Danazol (therapeutic use)
• Female
• Humans
• Immunoglobulin M (blood)
• Immunosuppressive Agents (therapeutic use)
• Ticlopidine (therapeutic use)
• Treatment Outcome