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Diagnosis of primary aldosteronism in chronic kidney disease by I-131 NP-59 SPECT/CT imaging.

Abstract
Primary aldosteronism (PA) may be missed in patients with chronic kidney disease (CKD), because CKD may disturb the renin-angiotensin-aldosterone system. Adrenal vein sampling has increased risks in patients with CKD. We report the case of a 58-year-old man with CKD and suspected PA. Left adrenal aldosteronism was diagnosed by NP-59 SPECT/CT. Left adrenalectomy demonstrated adrenocortical nodular hyperplasia. Plasma aldosterone normalized and blood pressure stabilized after surgery. NP-59 SPECT/CT may be a helpful diagnostic tool for detecting and lateralizing PA in CKD patients.
AuthorsYi-Chun Chen, Yu-Chieh Su, Jainn-Shiun Chiu, Chih-En Tseng
JournalClinical nuclear medicine (Clin Nucl Med) Vol. 37 Issue 2 Pg. e30-2 (Feb 2012) ISSN: 1536-0229 [Electronic] United States
PMID22228361 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Iodine Radioisotopes
  • Adosterol
Topics
  • Adosterol
  • Humans
  • Hyperaldosteronism (complications, diagnostic imaging)
  • Iodine Radioisotopes
  • Kidney Failure, Chronic (complications, diagnostic imaging)
  • Male
  • Middle Aged
  • Multimodal Imaging
  • Positron-Emission Tomography
  • Tomography, X-Ray Computed

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