HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Alpha-thalassemia: prenatal diagnosis and neonatal implications.

Abstract
Homozygous alpha-thalassemia major, or Bart's hemoglobinopathy, is the most common etiology of nonimmune hydrops in those of Oriental descent. The prenatal diagnosis can now be made utilizing DNA hybridization technique from fetal cells obtained by either amniocentesis or chorionic villus sampling. A case is reviewed documenting the utilization of DNA studies in managing patients known or suspected to have a history of alpha-thalassemia major.
AuthorsM C Maberry, V R Klein, C Boehm, T C Warren, L C Gilstrap 3rd
JournalAmerican journal of perinatology (Am J Perinatol) Vol. 7 Issue 4 Pg. 356-8 (Oct 1990) ISSN: 0735-1631 [Print] United States
PMID2222628 (Publication Type: Case Reports, Journal Article)
Chemical References
  • DNA
Topics
  • Adult
  • DNA (analysis)
  • Female
  • Humans
  • Hydrops Fetalis (etiology)
  • Nucleic Acid Hybridization
  • Pregnancy
  • Prenatal Diagnosis (methods)
  • Thalassemia (complications, diagnosis)
  • Vietnam (ethnology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: