[Peritoneal lavage cytology under local anesthesia for detection of peritoneal recurrence after surgery].

Abstract

Gastric cancer with positive peritoneal lavage cytology shows a very poor prognosis due to frequent peritoneal recurrence after surgery. Therefore, we have introduced neoadjuvant intra-peritoneal and systemic chemotherapy( NIPS) for gastric cancer with peritoneal microscopic and/or microscopic dissemination before surgery. In patients subjected to the strategy, we have experienced two cases of advanced gastric cancer with CY1, which had been treated with NIPS and curative surgery, had been performed with second peritoneal lavage cytology two years after surgery. In those two cases, S-1 was discontinued due to the negative results of peritoneal lavage cytology. We will present the cases.

• Authors: Kaoru Okada, Yoshiyuki Fujiwara, Tsuyoshi Takahashi, Yukinori Kurokawa, Makoto Yamasaki, Hiroshi Miyata, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 38 Issue 12 Pg. 2363-5 (Nov 2011) ISSN: 0385-0684 [Print] Japan
• PMID: 22202383 (Publication Type: Case Reports, Journal Article)

Chemical References

• Drug Combinations
• Taxoids
• S 1 (combination)
• Tegafur
• Docetaxel
• Oxonic Acid

Topics

• Aged
• Anesthesia, Local
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Docetaxel
• Drug Combinations
• Humans
• Male
• Middle Aged
• Neoadjuvant Therapy
• Oxonic Acid (administration & dosage, therapeutic use)
• Peritoneal Lavage
• Peritoneal Neoplasms (drug therapy, pathology, secondary, therapy)
• Recurrence
• Stomach Neoplasms (drug therapy, pathology, surgery)
• Taxoids (administration & dosage, therapeutic use)
• Tegafur (administration & dosage, therapeutic use)
• Tomography, X-Ray Computed