[A case of huge liver metastases from the colon cancer suffered from abdominal pain (an amount of LDH was beyond 4,000 IU/L)].

Abstract

We report a case suffered from an abdominal pain with huge hepatic metastases from the colon cancer. After laparoscopic partial colectomy with a three-time treatment of high dose hepatic arterial infusion by 5-FU (HDHAI), the tumor was decreased in size. Unfortunately she had an infectious pseudoaneurysm at the site of puncture. She was given with a drainage and F-F bypass. She has at last successfully done hepatectomy, radiofrequency ablation (RFA), and insertion of catheter at the site of common hepatic artery from gastroepiploic artery. Then she received a half HDHAI and systemic chemotherapy of CPT-11. However, residual liver metastases happened twice, but we could have them operated all (9.3 months after and 20.5 months after from first operation). If the liver metastases were the most threatening factor of life, HDHAI and repeated hepatectomy maybe effective for prolongation of life.

• Authors: Yasunori Hasuike, Ichiro Higuchi, Makoto Yamamoto, Atsuya Okada, Takahiko Tanigawa
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 38 Issue 12 Pg. 2033-5 (Nov 2011) ISSN: 0385-0684 [Print] Japan
• PMID: 22202275 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Lactate Dehydrogenases

Topics

• Abdominal Pain (etiology)
• Colonic Neoplasms (blood, complications, pathology, therapy)
• Combined Modality Therapy
• Female
• Hepatic Artery
• Humans
• Infusions, Intra-Arterial
• Lactate Dehydrogenases (blood)
• Liver Neoplasms (blood, enzymology, secondary, therapy)
• Middle Aged
• Tomography, X-Ray Computed