[Pregnancy in diabetes insipidus--a case report with review of the literature].

Abstract

A 32 year old I P II G with preexisting diabetes insipidus was treated with 1-(3-mercaptopropionic acid)-8-d-arginine vasopressin (DDAVP) during pregnancy. An otherwise normal pregnancy was marked only with an excessive weight increase. A healthy girl was delivered by secondary cesarean section at term. Postoperative the mother developed a water intoxication accompanying oxytocin-infusion. During nursing the diabetes insipidus improved significantly whereby DDAVP doses could be reduced to 20-10 percent. We suppose an overreaction to endogene oxytocin with an antidiuretic effect.

• Authors: R Cap, K P Lüscher
• Journal: Zentralblatt fur Gynakologie (Zentralbl Gynakol) Vol. 112 Issue 12 Pg. 773-8 ( 1990) ISSN: 0044-4197 [Print] Germany
• Vernacular Title: Schwangerschaft bei Diabetes Insipidus--ein Fallbericht mit Literaturübersicht.
• PMID: 2220171 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Oxytocin
• Deamino Arginine Vasopressin

Topics

• Administration, Intranasal
• Cesarean Section
• Deamino Arginine Vasopressin (administration & dosage)
• Diabetes Insipidus (drug therapy)
• Female
• Humans
• Infant, Newborn
• Oxytocin (adverse effects)
• Postoperative Complications (etiology)
• Pregnancy
• Pregnancy Complications (drug therapy)
• Water Intoxication (chemically induced)
• Water-Electrolyte Balance (drug effects)