[The antiviral efficacy of ribamidil in an experimental infection of animals with the Venezuelan equine encephalomyelitis virus].

Abstract

Considerable differences in antiviral efficacy of ribamydil were demonstrated in various animals experimentally infected with Venezuelan equine encephalomyelitis virus. The infection in baboons was quite similar to the manifestations of this disease in man as reported in the literature. With ribamydil used prophylactically, manifestations of the infection in monkeys were less marked.

• Authors: V A Markin, Iu G Pashanin, V I Markov, I A Androshchuk, V A Pshenichnov
• Journal: Voprosy virusologii (Vopr Virusol) 1990 May-Jun Vol. 35 Issue 3 Pg. 237-40 ISSN: 0507-4088 [Print] Russia (Federation)
• Vernacular Title: Protivovirusnaia éffektivnost' ribamidila pri éksperimental'noĭ infektsii zhivotnykh, zarazhennykh virusom venesuél'skogo éntsefalomielita loshadeĭ.
• PMID: 2219858 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Ribavirin

Topics

• Animals
• Chlorocebus aethiops
• Drug Evaluation, Preclinical
• Encephalomyelitis, Venezuelan Equine (drug therapy, mortality, prevention & control)
• Guinea Pigs
• Macaca fascicularis
• Papio
• Rabbits
• Ribavirin (therapeutic use)