[The prevention of chickenpox in high risk children. Comparison of the effectiveness of specific immunoglobulins and of defibrinated convalescent plasma. 414 cases (author's transl)].

Comparison between 157 children treated with defibrinated convalescent plasma and 257 children treated with specific immunoglobulins revealed the improved effectiveness of the latter treatment in the prevention of chickenpox. Specific Herpes Zoster-Chickenpox immunoglobulins are prepared by caprylic acid fractionation of convalescent plasma. The prevention obtained in more than 90% of cases would appear to be clinically and biologically total as shown by serological surveillance of certain children with particularly severe immune depression.
AuthorsG Avenard, M Gaiffe, F Herzog
JournalLa Nouvelle presse meĢdicale (Nouv Presse Med) Vol. 8 Issue 9 Pg. 673-5 (Feb 24 1979) ISSN: 0301-1518 [Print] FRANCE
Vernacular TitlePrévention de la varicelle chez les enfants à haut risque. Efficacité comparée des immunoglobulines spécifiques et du plasma défibriné de convalescent (414 cas).
PMID221885 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Immunoglobulins
  • Chickenpox (prevention & control)
  • Child
  • Convalescence
  • Herpesvirus 3, Human (immunology)
  • Humans
  • Immunization, Passive (methods)
  • Immunoglobulins (isolation & purification, therapeutic use)

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