Mast-cell leukemia exome sequencing reveals a mutation in the IgE mast-cell receptor β chain and KIT V654A.

• Authors: M S Spector, I Iossifov, A Kritharis, C He, J E Kolitz, S W Lowe, S L Allen
• Journal: Leukemia (Leukemia) Vol. 26 Issue 6 Pg. 1422-5 (Jun 2012) ISSN: 1476-5551 [Electronic] England
• PMID: 22173243 (Publication Type: Case Reports, Letter, Research Support, Non-U.S. Gov't)

Chemical References

• Biomarkers, Tumor
• Receptors, IgE
• Proto-Oncogene Proteins c-kit

Topics

• Adult
• Biomarkers, Tumor (genetics)
• Exome (genetics)
• Female
• Gene Expression Profiling
• Humans
• Leukemia, Mast-Cell (genetics)
• Mutation (genetics)
• Oligonucleotide Array Sequence Analysis
• Polymorphism, Single Nucleotide (genetics)
• Proto-Oncogene Proteins c-kit (genetics)
• Receptors, IgE (genetics)
• Sequence Analysis, DNA