[The risk of post-transfusion hemolytic complications in rhesus-positive patients and the ways of their prevention].

Abstract

The minor antigen "c" of the rhesus system, which is revealed in population both in rhesus-negative and in rhesus-positive person with 80% frequency, is considered highly immunogenic, it causes severe hemolytic complications while hemotransfusion. In pregnant women it causes the immune conflict and, as a consequence, a hemolytic disease of newborn babies, demanding the treatment, using exchanging blood transfusion (erythrocytes). For the immune conflict prevention it is obligatory to determine the rhesus phenotype in donor and recipient as well as to investigate the presence of alloisoimmune antibodies in a recipient. In hemolytic disease of newborn baby the titer of antibodies towards erythrocytes in a parturient woman blood serum is obligatory estimated with individual matching of erythrocyte-containing media for the exchanging transfusion to newborn baby.

• Authors: G M Dizik, R P Pavliuk
• Journal: Klinichna khirurhiia (Klin Khir) Issue 9 Pg. 69-72 (Sep 2011) ISSN: 0023-2130 [Print] Ukraine
• PMID: 22168031 (Publication Type: Case Reports, Journal Article)

Chemical References

• Isoantibodies
• Minor Histocompatibility Antigens
• Rh-Hr Blood-Group System

Topics

• Adult
• Blood Group Incompatibility (blood, immunology, prevention & control)
• Blood Grouping and Crossmatching
• Blood Transfusion (methods)
• Erythrocyte Transfusion (adverse effects, methods)
• Female
• Hemolysis (immunology)
• Humans
• Isoantibodies (blood)
• Minor Histocompatibility Antigens (immunology)
• Pregnancy
• Pregnancy Complications, Hematologic (blood)
• Rh-Hr Blood-Group System (immunology)
• Transfusion Reaction
• Treatment Outcome