[Efficacy of tribendimdine in treatment of hookworm infection].

Abstract

OBJECTIVE:

To study the efficacy of tribendimdine in the treatment of hookworm infection.

METHODS:

Forty-seven cases of hookworm infection detected in a cross-sectional study were selected and randomly divided into two groups, one was experimental group (23 cases) treated with tribendimdine and the other was control group (24 cases) treated with albendazole. The negative conversion rates and the incidence rates of adverse effects in the two groups were observed and compared.

RESULTS:

The negative conversion rates and the incidence rates of adverse effects of the two groups were 95.65% and 95.83%, 8.70% and 8.33%, respectively, there were no statistical differences (both P values > 0.05).

CONCLUSION:

The efficacy of tribendimdine in the treatment of hookworm infection is similar to albendazole.

• Authors: Li-Guang Tian, Guo-Jin Cheng, Feng-Feng Wang, Jian Guo, Yu-Chun Cai, Tian-Ping Wang, Jia-Xu Chen, Xiao-Nong Zhou
• Journal: Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control (Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi) Vol. 23 Issue 2 Pg. 202-3 (Apr 2011) ISSN: 1005-6661 [Print] China
• PMID: 22164629 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Anthelmintics
• Phenylenediamines
• tribendimidine
• Albendazole

Topics

• Adolescent
• Adult
• Aged
• Albendazole (therapeutic use)
• Ancylostomatoidea (drug effects, physiology)
• Animals
• Anthelmintics (therapeutic use)
• Child
• Female
• Hookworm Infections (drug therapy, parasitology)
• Humans
• Male
• Middle Aged
• Phenylenediamines (therapeutic use)
• Young Adult