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Effect of plasmapheresis on serum and CSF autoantibody levels in CNS paraneoplastic syndromes.

Abstract
We compared the effect of plasmapheresis on antineuronal autoantibody titers in the serum and CSF of 3 patients with CNS paraneoplastic syndromes. Plasmapheresis reduced the serum autoantibody titer to 20% of the initial levels in the 3 patients, but the CSF autoantibody titer decreased only in the patient with severe damage of the blood-brain barrier.
AuthorsF Graus, J Abos, J Roquer, R Mazzara, A Pereira
JournalNeurology (Neurology) Vol. 40 Issue 10 Pg. 1621-3 (Oct 1990) ISSN: 0028-3878 [Print] United States
PMID2215957 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Autoantibodies
Topics
  • Aged
  • Autoantibodies (analysis, cerebrospinal fluid)
  • Central Nervous System Diseases (immunology, therapy)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paraneoplastic Syndromes (immunology, therapy)
  • Plasmapheresis
  • Time Factors

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