Abstract | OBJECTIVE: METHODS: Patients with a clinical diagnosis of plantar fasciitis made at least six months earlier were selected to enter a randomized, single-blind study of treatment with injections of botulinum toxin type A or corticosteroid. There were 28 patients in each treatment group. Patients were evaluated at one month using the Foot Health Square Questionnaire and those with no clinical response subsequently received a second injection with the drug of the other arm of the study, creating two new treatment groups. Re-evaluation was performed at six months. RESULTS: One month after injection there was a clear clinical improvement in both treatment groups but it was greater in the botulinum toxin group, with a significant difference for the pain item (P = 0.069), though not in other items. At six months, patients treated with botulinum toxin type A had continued to improve in all items, whereas the corticosteroid group lost part of the improvement achieved at one month (improvement with botulinum toxin vs. corticosteroid: pain 19.10/-6.84 (P = 0.001), function 16.00/-8.80 (P < 0.001), footwear 13.48/-7.95 (P = 0.004), self-perceived foot health 25.44/-5.41 (P < 0.001). CONCLUSION:
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Authors | Ismael V Díaz-Llopis, Carmen M Rodríguez-Ruíz, Sandra Mulet-Perry, Francisco J Mondéjar-Gómez, Jose M Climent-Barberá, Francisco Cholbi-Llobel |
Journal | Clinical rehabilitation
(Clin Rehabil)
Vol. 26
Issue 7
Pg. 594-606
(Jul 2012)
ISSN: 1477-0873 [Electronic] England |
PMID | 22144721
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Adrenal Cortex Hormones
- Neuromuscular Agents
- Botulinum Toxins, Type A
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Topics |
- Adrenal Cortex Hormones
(administration & dosage, therapeutic use)
- Botulinum Toxins, Type A
(administration & dosage, therapeutic use)
- Fasciitis, Plantar
(drug therapy)
- Female
- Humans
- Injections, Intramuscular
(methods)
- Male
- Middle Aged
- Neuromuscular Agents
(administration & dosage, therapeutic use)
- Pain
(drug therapy)
- Single-Blind Method
- Time
- Treatment Outcome
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