Outcomes of a cancer clinical trial matching service.

Abstract

The American Cancer Society (ACS) and Coalition of Cancer Cooperative Groups (CCCG) provide a clinical trial (CT) information/matching/eligibility service (Clinical Trials Matching Service [CTMS]). Patients' demographic and clinical data, enrollment status, and self-reported barriers to CT participation were analyzed to assess enrollment rates and determinants of enrollment. During 3 years beginning October 1, 2007, the CTMS served 6,903 patients via the ACS call center. Among the 1,987 patients with follow-up information on enrollment, 219 (11.0%) enrolled in a CT; 48 of these 219 enrollees chose a CT they found via the CTMS. Patients were less likely to enroll if they had poor ECOG performance status (P = 0.032); were African American (P = 0.0003), were uninsured or had Medicaid coverage (P = 0.024), or had lower stage disease (P = 0.018). Enrollment varied by trial type/cancer site/system (P = .026). Several barriers significantly predicted nonenrollment. Broader availability of a CTMS might help improve patient participation in cancer clinical trials.

• Authors: Ted Gansler, Man Jin, Joseph Bauer, Katie Dahlquist, Larissa Tis, Katherine Sharpe, Robert Comis, Kimberly Naples, James Kepner
• Journal: Journal of cancer education : the official journal of the American Association for Cancer Education (J Cancer Educ) Vol. 27 Issue 1 Pg. 11-20 (Mar 2012) ISSN: 1543-0154 [Electronic] England
• PMID: 22131066 (Publication Type: Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Child
• Child, Preschool
• Clinical Trials as Topic (statistics & numerical data)
• Female
• Health Services Accessibility
• Humans
• Infant
• Infant, Newborn
• Male
• Middle Aged
• Minority Groups (statistics & numerical data)
• Neoplasms (prevention & control)
• Patient Participation
• Patient Selection
• Prognosis
• White People (statistics & numerical data)
• Young Adult