Abstract |
In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond 48 h after hospital admission, are associated with a worse prognosis. Several comprehensive reviews of the investigation and management of encephalitis have been published. However, their impact on day-to-day clinical practice appears to be limited. The emergency management of meningitis in children and adults was revolutionised by the introduction of a simple algorithm as part of management guidelines. In February 2008 a group of clinicians met in Liverpool to begin the development process for clinical care guidelines based around a similar simple algorithm, supported by an evidence base, whose implementation is hoped would improve the management of patients with suspected encephalitis.
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Authors | R Kneen, B D Michael, E Menson, B Mehta, A Easton, C Hemingway, P E Klapper, A Vincent, M Lim, E Carrol, T Solomon, National Encephalitis Guidelines Development and Stakeholder Groups |
Journal | The Journal of infection
(J Infect)
Vol. 64
Issue 5
Pg. 449-77
(May 2012)
ISSN: 1532-2742 [Electronic] England |
PMID | 22120594
(Publication Type: Journal Article, Practice Guideline)
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Copyright | Copyright © 2012. Published by Elsevier Ltd. |
Chemical References |
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Topics |
- Adolescent
- Antiviral Agents
(therapeutic use)
- Child
- Child, Preschool
- Encephalitis, Viral
(diagnosis, drug therapy, epidemiology, virology)
- Female
- Humans
- Infant
- Infant, Newborn
- Male
- United Kingdom
(epidemiology)
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