CASE: A 53-year-old woman visited a local doctor because of decreased vision OS. Fundus examination of the left eye revealed
hyperemia and swelling of the optic disc as well as
retinal vasculitis. She was treated with systemic
corticosteroids. However, since there was no improvement in the ocular findings, she was referred to the Department of Ophthalmology of Tokyo Medical University Hospital. At presentation, mild anterior segment
inflammation was observed, together with sheathing mainly of the veins as well as
hyperemia and swelling of the optic disc in the fundus. Because the patient did not respond to
corticosteroid treatment and the subretinal exudative lesion around the optic disc subsequently worsened,
intraocular lymphoma was suspected. Diagnostic
vitrectomy was performed. The vitreous cytology was class III. Although polymerase chain reaction detected no immunoglobulin gene rearrangement,
interleukin (IL)-10 was 4290 pg/ml and
IL-6 was 94 pg/ml in the vitreous fluid. Based on these data and the
clinical course, the diagnosis of
intraocular lymphoma was made. Shortly after
radiotherapy to the eyeball, the optic disk findings improved and the
retinal vasculitis was resolved; visual acuity improved as well.
CONCLUSION: