Liver transplantation for refractory severe pruritus related to widespread multifocal hepatic focal nodular hyperplasia (FNH) in a child: case report and review of literature.

Abstract

FNH is a rare and benign tumor of the liver. It is not a conventional indication for liver transplantation, and no transplant for FNH in a child has been reported to date. Multifocal FNH growing in adolescent age to a widespread tumor invading the whole liver and associated with severe refractory pruritus was an unusual indication for transplantation in a 13-yr-old girl. The operation and the follow-up were uneventful, allowing full recovery and disappearance of pruritus.

• Authors: L Merli, C Grimaldi, L Monti, V Nobili, P Francalanci, J de Ville de Goyet
• Journal: Pediatric transplantation (Pediatr Transplant) Vol. 16 Issue 7 Pg. E265-8 (Nov 2012) ISSN: 1399-3046 [Electronic] Denmark
• PMID: 22093884 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: © 2011 John Wiley & Sons A/S.

Topics

• Adolescent
• Child
• Female
• Focal Nodular Hyperplasia (complications, therapy)
• Humans
• Liver (abnormalities, pathology)
• Liver Transplantation (methods)
• Pruritus (therapy)
• Tomography, X-Ray Computed (methods)
• Treatment Outcome