Febrile ulceronecrotic Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) presenting as Stevens-Johnson syndrome.

Abstract

We present two pediatric patients with pityriasis lichenoides et varioliformis acuta fulminans whose admitting diagnosis was Stevens Johnson Syndrome. The patients were successfully treated with methotrexate and prednisone. These cases highlight the importance of early recognition and treatment of this disease to prevent further morbidity and a potentially fatal prognosis.

• Authors: William S Kaufman, Elizabeth K McNamara, Ashley R Curtis, Payman Kosari, Joseph L Jorizzo, Daniel P Krowchuk
• Journal: Pediatric dermatology (Pediatr Dermatol) Vol. 29 Issue 2 Pg. 135-40 ( 2012) ISSN: 1525-1470 [Electronic] United States
• PMID: 22084981 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: © 2011 Wiley Periodicals, Inc.

Chemical References

• Anti-Bacterial Agents
• Dermatologic Agents
• Clindamycin
• Vancomycin
• Prednisone
• Methotrexate

Topics

• Anti-Bacterial Agents (therapeutic use)
• Clindamycin (therapeutic use)
• Dermatologic Agents (therapeutic use)
• Drug Therapy, Combination
• Female
• Herpes Simplex (diagnosis, drug therapy)
• Humans
• Infant
• Methotrexate (therapeutic use)
• Pityriasis Lichenoides (diagnosis, drug therapy)
• Prednisone (therapeutic use)
• Skin Ulcer (diagnosis, drug therapy)
• Stevens-Johnson Syndrome (diagnosis)
• Treatment Outcome
• Vancomycin (therapeutic use)