The laboratory of clinical virology in monitoring patients undergoing monoclonal antibody therapy.

Abstract

The relevant efficacy of monoclonal antibodies (mAbs) has resulted in the successful treatment of several diseases, although susceptibility to infections remains a major problem. This review summarizes aspects of the literature regarding viral infections and mAbs, specifically addressing the risk of infection/reactivation, the measures that can reduce this risk, and the role played by the laboratory of clinical virology in monitoring patients undergoing mAb therapy.

• Authors: R Cavallo
• Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (Clin Microbiol Infect) Vol. 17 Issue 12 Pg. 1781-5 (Dec 2011) ISSN: 1469-0691 [Electronic] England
• PMID: 22082209 (Publication Type: Journal Article, Review)
• Copyright: © 2011 The Author. Clinical Microbiology and Infection © 2011 European Society of Clinical Microbiology and Infectious Diseases.

Chemical References

• Antibodies, Monoclonal
• Immunosuppressive Agents

Topics

• Antibodies, Monoclonal (adverse effects, therapeutic use)
• Clinical Laboratory Techniques (methods)
• Drug Monitoring (methods)
• Humans
• Immunosuppressive Agents (adverse effects, therapeutic use)
• Opportunistic Infections (chemically induced, diagnosis)
• Virology (methods)
• Virus Activation
• Virus Diseases (chemically induced, diagnosis)