HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Hypoxia: developments in basic science, physiology and clinical studies.

Abstract
Airway management is primarily designed to avoid hypoxia, yet hypoxia remains the main ultimate cause of anaesthetic-related death and morbidity. Understanding some of the physiology of hypoxia is therefore essential as part of a 'holistic' approach to airway management. Furthermore, it is strategically important that national specialist societies dedicated to airway management do not only focus upon the technical aspects of airway management, but also embrace some of the relevant scientific questions. There has been a great deal of research into causation of hypoxia and the body's natural protective mechanisms and responses to it. This enables us to think of ways in which we might manipulate the cellular and molecular responses to confer greater protection against hypoxia-induced tissue injury. This article reviews some of those aspects.
AuthorsD S Ward, S B Karan, J J Pandit
JournalAnaesthesia (Anaesthesia) Vol. 66 Suppl 2 Pg. 19-26 (Dec 2011) ISSN: 1365-2044 [Electronic] England
PMID22074075 (Publication Type: Journal Article, Review)
Copyright© 2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.
Chemical References
  • Analgesics, Opioid
  • Anesthetics, Inhalation
Topics
  • Adaptation, Physiological (physiology)
  • Airway Management (methods)
  • Analgesics, Opioid (adverse effects)
  • Anesthesia Recovery Period
  • Anesthesia, Inhalation
  • Anesthetics, Inhalation (pharmacology)
  • Humans
  • Hypoxia (etiology, physiopathology, therapy)
  • Mitochondria (metabolism, physiology)
  • Pulmonary Atelectasis (chemically induced, physiopathology)
  • Respiration, Artificial
  • Respiratory Mechanics (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: