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Co-enzyme Q10: a new drug for cardiovascular disease.

Abstract
Co-enzyme Q10 (ubiquinone) is a naturally occurring substance which has properties potentially beneficial for preventing cellular damage during myocardial ischemia and reperfusion. It plays a role in oxidative phosphorylation and has membrane stabilizing activity. The substance has been used in oral form to treat various cardiovascular disorders including angina pectoris, hypertension, and congestive heart failure. Its clinical importance is now being established in clinical trails worldwide.
AuthorsS Greenberg, W H Frishman
JournalJournal of clinical pharmacology (J Clin Pharmacol) Vol. 30 Issue 7 Pg. 596-608 (Jul 1990) ISSN: 0091-2700 [Print] England
PMID2202752 (Publication Type: Journal Article, Review)
Chemical References
  • Coenzymes
  • Free Radicals
  • Ubiquinone
  • Doxorubicin
  • coenzyme Q10
Topics
  • Administration, Oral
  • Cardiovascular Diseases (drug therapy)
  • Chemical Phenomena
  • Chemistry
  • Coenzymes
  • Doxorubicin (antagonists & inhibitors)
  • Free Radicals
  • Heart Arrest, Induced
  • Heart Failure (drug therapy)
  • Humans
  • Hypertension (drug therapy)
  • Ischemia (drug therapy)
  • Reperfusion
  • Ubiquinone (analogs & derivatives, pharmacokinetics, pharmacology, therapeutic use)

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