[Opiates do not guarantee an adequate analgesia after large-volume open operations on the abdominal cavity organs].

Abstract

Efficacy of systemic application of opiates (promedol) for the pain relief after big open abdominal operations, using visual-analogue scale (VAS), was estimated in 50 patients. During 36-48 h postoperatively analgesia was inadequate (VAS in a rest state more than 3 points and while movement--more than 4 points). Intensive pain (VAS 6 points and more) was noted in 58% of patients, while they are moving, and in 26%--in a rest state. Inadequate anesthesia may constitute one of causes of excessive systemic inflammatory reaction development in patients postoperatively.

• Authors: A L Potapov, Iu Iu Kobeliatskiĭ
• Journal: Klinichna khirurhiia (Klin Khir) Issue 8 Pg. 28-31 (Aug 2011) ISSN: 0023-2130 [Print] Ukraine
• PMID: 22013685 (Publication Type: English Abstract, Journal Article)

Chemical References

• Analgesics, Opioid
• Promedol
• C-Reactive Protein

Topics

• Abdominal Cavity (surgery)
• Analgesia (methods)
• Analgesics, Opioid (administration & dosage, adverse effects, therapeutic use)
• C-Reactive Protein (analysis)
• Digestive System Surgical Procedures (methods)
• Humans
• Middle Aged
• Pain Measurement
• Pain, Postoperative (prevention & control)
• Promedol (administration & dosage, adverse effects, therapeutic use)
• Prospective Studies
• Time Factors
• Treatment Outcome