Abstract | OBJECTIVE: DATA SOURCES: STUDY SELECTION AND DATA EXTRACTION: All reports on the use of lacosamide in patients with status epilepticus were included for evaluation. Reviews and animal data were excluded. DATA SYNTHESIS: Treatment of status epilepticus is challenging, and most patients fail to respond to initial treatment. Recently, several reports have been published on the use of lacosamide for status epilepticus. Eleven reports (5 case reports and 6 case series) were identified. Lacosamide was credited with successful termination of status epilepticus in a majority of these reports. However, the data are weakened by the heterogeneity of the reports, their descriptive nature, and the common divergence from current recommendations for the treatment of status epilepticus. CONCLUSIONS:
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Authors | Erica M Fernandez, Andrew J Franck |
Journal | The Annals of pharmacotherapy
(Ann Pharmacother)
Vol. 45
Issue 11
Pg. 1445-9
(Nov 2011)
ISSN: 1542-6270 [Electronic] United States |
PMID | 22010001
(Publication Type: Journal Article, Review)
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Chemical References |
- Acetamides
- Anticonvulsants
- Lacosamide
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Topics |
- Acetamides
(therapeutic use)
- Anticonvulsants
(therapeutic use)
- Humans
- Lacosamide
- Status Epilepticus
(drug therapy)
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