Long-term results of botulinum toxin-augmented medial rectus recessions for large-angle infantile esotropia.

Abstract

PURPOSE:

To evaluate the long-term results of medial rectus recessions augmented by botulinum toxin injection for treating infants with large-angle (> 60 prism diopters [PD]) infantile esotropia.

DESIGN:

Interventional case series.

METHODS:

SETTINGS:

Hospital-based clinical practice.

PATIENT POPULATION:

Twenty-three patients with large-angle infantile esotropia who were followed for at least 2 years postoperatively.

INTERVENTION:

Surgical treatment with botulinum toxin in addition to bilateral medial rectus muscle recessions. The preoperative findings, treatment, and outcomes were reviewed.

MAIN OUTCOME MEASURES:

Surgery was considered successful if the patients did not require additional horizontal strabismus surgery and had less than 10 PD of horizontal deviation.

RESULTS:

The age at surgery ranged from 4 to 36 months (mean 14.5 months) and the angle of esotropia ranged from 65 to 100 PD (mean 72 PD). Treatment was successful in 17 of 23 patients (74%), with follow-up of 2 to 13 years (mean 6.6 years).

CONCLUSION:

Botulinum toxin-augmented medial rectus recession is an effective treatment for large-angle infantile esotropia, with stable results over time.

• Authors: Gregg T Lueder, Marlo Galli, Lawrence Tychsen, Cem Yildirim, Victor Pegado
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 153 Issue 3 Pg. 560-3 (Mar 2012) ISSN: 1879-1891 [Electronic] United States
• PMID: 21996305 (Publication Type: Journal Article)
• Copyright: Copyright © 2012 Elsevier Inc. All rights reserved.

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Botulinum Toxins, Type A (administration & dosage)
• Child, Preschool
• Combined Modality Therapy
• Esotropia (drug therapy, physiopathology, surgery, therapy)
• Follow-Up Studies
• Humans
• Infant
• Neuromuscular Agents (administration & dosage)
• Oculomotor Muscles (drug effects, surgery)
• Ophthalmologic Surgical Procedures
• Prognosis
• Retrospective Studies
• Vision, Binocular (physiology)