Abstract | OBJECTIVE: STUDY DESIGN: Prospective clinical study. SETTING: University hospital. SUBJECTS AND METHODS: The present study includes 8 patients with Bell palsy and 5 with herpes zoster oticus showing facial synkinesis. A single dose of botulinum A toxin was used as the initial process of facial rehabilitation. Patients then continued a daily facial biofeedback rehabilitation with a mirror at home. They were instructed to keep their eyes symmetrically open using a mirror during mouth movements. The degree of oral-ocular synkinesis was evaluated by the degree of asymmetry of eye opening width during mouth movements (% eye opening). RESULTS: After administration of a single dose of botulinum A toxin, temporary relief of facial synkinesis was observed in all patients. Patients were then instructed to continue the facial biofeedback rehabilitation with a mirror for 10 months. The mean values of the percent of eye opening during 3 designated mouth movements that included lip pursing /u:/, teeth baring /i:/, and cheek puffing /pu:/ increased significantly after 10 months when the effects of botulinum A toxin had completely disappeared. CONCLUSION:
|
Authors | Takahiro Azuma, Katsuhiko Nakamura, Mika Takahashi, Seizo Ohyama, Naoki Toda, Hidetaka Iwasaki, Bukasa Kalubi, Noriaki Takeda |
Journal | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
(Otolaryngol Head Neck Surg)
Vol. 146
Issue 1
Pg. 40-5
(Jan 2012)
ISSN: 1097-6817 [Electronic] England |
PMID | 21965443
(Publication Type: Clinical Trial, Comparative Study, Journal Article)
|
Chemical References |
- Neuromuscular Agents
- Botulinum Toxins, Type A
|
Topics |
- Adult
- Aged
- Biofeedback, Psychology
(drug effects)
- Botulinum Toxins, Type A
(administration & dosage)
- Chronic Disease
- Dose-Response Relationship, Drug
- Face
- Facial Muscles
(physiopathology)
- Facial Paralysis
(complications, drug therapy, physiopathology)
- Female
- Follow-Up Studies
- Humans
- Injections, Intramuscular
- Male
- Middle Aged
- Muscle Contraction
(drug effects, physiology)
- Neuromuscular Agents
(administration & dosage)
- Prospective Studies
- Synkinesis
(drug therapy, etiology, physiopathology)
- Treatment Outcome
|