[Synergic effect of alprostadil injection and ginaton in treating sudden deafness].

Abstract

OBJECTIVE:

To explore synergic effect of Alprostadil injection and ginaton in treating sudden deafness.

METHOD:

ninety one patients with sudden deafness were divided into group A, group B and group C at random; 33 ears of group A were treated with 70 mg ginaton by vein, 30 ears of group B were treated with 10 microg Alprostadil injection by vein, 31 ears of group C were treated with 10 microg Alprostadil injection and ginaton by vein,once a day, the time of treatment is 14 days.

RESULT:

the effective rate of group A is 60.61%, the effective rate of group B is 60.00%, the effective rate of group C is 87.09% the treating effect was significantly different in the group A and C (P < 0.05), it was significantly different in the group B and C (P < 0.05)).

CONCLUSION:

It is effective for Alprostadil injection and ginaton to treat sudden deafness, and it has significantly Synergic effect in treating sudden deafness with Alprostadil injection and ginaton.

• Authors: Jiping Jiang, Shuyun Wang, Kang Tong
• Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery (Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi) Vol. 25 Issue 13 Pg. 597-9 (Jul 2011) ISSN: 2096-7993 [Print] China
• PMID: 21949991 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Drugs, Chinese Herbal
• ginaton
• Alprostadil

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Alprostadil (administration & dosage, therapeutic use)
• Drug Therapy, Combination
• Drugs, Chinese Herbal (administration & dosage, therapeutic use)
• Female
• Hearing Loss, Sudden (drug therapy)
• Humans
• Male
• Middle Aged
• Young Adult